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Diablo 4 Vessel of Hatred: All Runes Tier List
The latest expansion for Diablo 4, Vessel of Hatred, has introduced the exciting return of Runes since the days of Diablo 2.
These power-ups allow players to enhance their gear with various combinations of runes that evolve into powerful Runewords, granting additional abilities. Whether you aim to wield the Sorcerer’s Teleport as a Necromancer or bolster specific weaknesses in your build, the Runeword system offers remarkable versatility and potency.
Discover all there is to know about the Runes and Runewords in Diablo 4: Vessel of Hatred.
In Vessel of Hatred, these special socketable stones bring a whole new dimension to your gear. While a single Rune won’t do much, combining two of them creates a powerful Runeword that lets you borrow skills from other classes. It may seem a bit complex at first, but it’s actually quite straightforward.
There are two categories of Runes to consider:
These Runes typically generate Offerings based on an action you perform, such as drinking a potion or casting an ultimate skill. Rarer variants tend to have easier trigger conditions.
For example, with Invocation Runes, you can summon spirit wolves, boost critical chance, or even unleash skills from other classes. Stronger abilities consume more offerings and are often linked to rarer Invocation Runes.
To make these Runes work, you’ll need to slot both a Ritual Rune and an Invocation Rune onto a two-slotted piece of gear, like your legs, helmet, chest, or two-handed weapon. If you happen to provide more Offerings than required for an Invocation Rune, you’ll trigger an additional Overflow effect.
To unlock Runeword in Diablo 4, you need to progress through the Vessel of Hatred campaign until you receive the quest “Fundament of Faith.” Upon completing this quest, an NPC will grant you the access to use the Runeword system and provide you with an initial set of Runes to start experimenting with.
You can obtain Runes in the Vessel of Hatred from various sources:
Additionally, you can craft Runes at the Jeweler by using 3 of the same type to generate a random Rune of the same rarity. You can also find Tributes in the Undercity and through other activities, which increase the Rune rewards you receive for completing the activity. Best to remember that the Undercity is the best place to farm for Runes.
Creating and using Runeword is quite simple. To do this, you need to socket a Ritual Rune and an Invocation Rune into the same piece of gear. The Ritual Rune serves as your generator, while the Invocation Rune is your spender. If done correctly, an icon should appear above your skill bar displaying the created Runeword. The icon’s background will gradually fill up as you generate Offering.
Once it is full, the Runeword will automatically trigger and reset your Offering. Keep in mind that you must socket both runes onto a single piece of gear, so any gear you intend to form a runeword on will need at least two sockets.
If you wish to change them, you can simply unsocket the runes from your equipment in your inventory without needing to visit the Jeweler. We suggest placing your Runeword in your helmet, body armor, or pants, as these pieces only accommodate stat-boosting gems. Also, ensure that the offering on the Ritual Rune is equal to or greater than the offering on the Invocation Rune.
This tier list showcases the best and worst-ranked Runes, ranging from Ritual Runes to Invocation Runes. Keep in mind that only two Runewords may be active at a time.
These Runes are the easiest to gather Offering with for Invocation Runes.
| Rune Name | Rarity | Offering Granted | Rune Description |
| Tam | Legendary | 25 Offering | Cast a non-channeled core skill. |
| Lith | Legendary | 25 Offering | Stand still for 0.3 seconds. |
| Poc | Rare | 2 Offering | Spend 5% of your Maximum Resource. |
| Xol | Legendary | 150 Offering | Invoke a skill from another class. |
| Yul | Legendary | 50 Offering | Cast a skill with a cooldown. |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Zan | Magic | 150 Offering | Cast an ultimate skill. |
| Bac | Legendary | 50 Offering | Travel 5 meters. |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Cir | Magic | 25 Offering | Cast the same non-channeled skill 3 times in a row. |
| Cem | Magic | 50 Offering | Cast evade. |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Noc | Rare | 5 Offering | Inflict a crowd control that isn’t slow or chill. |
| Neo | Rare | 300 Offering | Deal damage after not taking any within 5 seconds. |
| Yax | Magic | 100 Offering | Drink a healing potion. |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Moni | Magic | 10 Offering | Cast a skill after moving, (Cooldown: 0.2 seconds) |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Ahu | Legendary | 10 Offering | Lucky Hit: up to a 100% chance against injured enemies. |
| Feo | Rare | 1000 Offering | Become injured or crowd controlled (Cooldown: 10 seconds) |
The best abilities to get for free regardless of Class are the Barb’s War Cry and Necro’s Decrepify.
| Rune Name | Rarity | Offering Granted | Rune Description |
| Ohm | Legendary | 600 Offering | Evoke the Barbarian’s War Cry skill. (Cooldown: 2 seconds) |
| Wat | Rare | 100 Offering | Evoke the Necromancer’s Decrepify skill. (Cooldown: 1 second) |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Mot | Rare | 150 Offering | Gain a shroud from the Rogue’s Dark Shadow skill. (Cooldown: 1 second) |
| Kry | Rare | 300 Offering | Evoke the Spiritborn’s Vortex skill. (Cooldown: 3 seconds) |
| Que | Rare | 300 Offering | Evoke the Druid’s Earthen Bulwark skill. (Cooldown: 1 second) |
| Gar | Magic | 25 Offering | Gain 2% critical chance for 5 seconds, up to 20%. (Cooldown: 1 second) |
| Tec | Magic | 100 Offering | Evoke the Barbarian’s Earthquake skill. (Cooldown: 1 second) |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Yom | Legendary | 500 Offering | Evoke the Druid’s Petrify skill. (Cooldown: 5 seconds) |
| Xan | Legendary | 100 Offering | Your next skill is guaranteed to overpower and critically strike. (Cooldown: 1 second) |
| Lac | Rare | 400 Offering | Evoke the Barbarian’s Challenging Shout skill. (Cooldown: 1 second) |
| Xal | Rare | 200 Offering | Gain 20% of Maximum Life for 4 seconds. (Cooldown: 1 second) |
| Tzic | Rare | 250 Offering | Evoke the Spiritborn’s Concussive Stomp skill. (Cooldown: 1 second) |
| Ton | Magic | 25 Offering | Evoke the Sorcerer’s Meteorites skill. (Cooldown: 1 second) |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Jah | Legendary | 400 Offering | Replace your next evade with Sorcerer’s Teleport skill. (Cooldown: 2 seconds) |
| Ceh | Magic | 100 Offering | Summon a Spirit Wolf to attack enemies for 8 seconds. (Cooldown: 1 second) |
| Lum | Magic | 5 Offering | Restore 1 Primary Resource. (Cooldown: 1 second) |
| Zec | Rare | 200 Offering | Reduce your active ultimate cooldown by 2 seconds. (Cooldown: 2 seconds) |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Vex | Legendary | 1000 Offering | Gain +3 to all skills for 5 seconds. (Cooldown: 1 second) |
| Qax | Rare | 400 Offering | Your next non-basic skill spends all primary resource to deal up to 100% more damage. (Cooldown: 1 second) |
| Qua | Rare | 50 Offering | Gain 5% movement speed, up to 30%. (Cooldown: 1 second) |
| Tal | Magic | 100 Offering | Evoke the Spiritborn’s Pestilent Swarm skill. (Cooldown: 1 second) |
| Teb | Magic | 100 Offering | Evoke the Necromancer’s Abhorrent Iron Maiden skill. |
| Rune Name | Rarity | Offering Granted | Rune Description |
| Eom | Legendary | 100 Offering | Reduce all cooldowns by 0.1 second. (Cooldown: 1 second) |
| Ner | Rare | 600 Offering | Evoke the Rogue’s Countering Concealment skill. (Cooldown: 6 seconds) |
| Thul | Rare | 400 Offering | Evoke the Sorcerer’s Mystical Frost Nova skill. (Cooldown: 2 seconds) |
| Tun | Magic | 100 Offering | Evoke the Rogue’s Stun Grenades skill. (Cooldown: 1 second) |
Diablo IV: Vessel of Hatred is now available for PlayStation 4, PlayStation 5, Xbox One, Xbox Series X/S, and PC via Steam. For more guides, check out the best builds for each class and the new Uniques and Mythical Uniques items.
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[…] For the best Runes set to equip for any Class, check out our tier list. […]